Discovery of a Novel Circular DNA Virus in the Forbes Sea Star, Asterias forbesi

Elizabeth Fahsbender, Ian Hewson, Karyna Rosario, Allison Tuttle, Arvind Varsani, Mya Breitbart

Research output: Contribution to journalArticlepeer-review

Abstract

<p> <p id="x-x-Par1"> A single-stranded DNA (ssDNA) virus, Asterias forbesi-associated circular virus (AfaCV), was discovered in a Forbes sea star displaying symptoms of sea star wasting disease (SSWD). The AfaCV genome organization is typical of circular Rep-encoding ssDNA (CRESS-DNA) viruses and is similar to that of members of the family <em> Circoviridae </em> . PCR-based surveys indicate that AfaCV is not clearly associated with SSWD, whereas the sea star-associated densovirus (SSaDV), recently implicated in SSWD in the Pacific, was prevalent in symptomatic specimens. AfaCV represents the first CRESS-DNA virus detected in echinoderms, adding to the growing diversity of these viruses recently recovered from invertebrates. </p></p>
Original languageAmerican English
JournalArchives of Virology
Volume160
DOIs
StatePublished - Jan 1 2015

Keywords

  • Whole Genome Amplification
  • Viral Metagenomics
  • Keystone Predator
  • Major Open Reading Frame
  • Viral Contigs

Disciplines

  • Life Sciences

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