Incident Tuberculosis Diagnoses in Children at High Risk for Disease

Milagros Wong, Julia M Coit, Milagros Mendoza, Silvia S Chiang, Helen Marin, Jerome T. Galea, Leonid Lecca, Molly F Franke

Research output: Contribution to journalArticlepeer-review

Abstract

We followed 35 children meeting a research definition for unconfirmed tuberculosis (TB) but in whom a pediatric pulmonologist did not diagnose or treat TB. After a median follow-up of 16.4 months, most children were not diagnosed with TB following a comprehensive evaluation. However, 2 were diagnosed with TB, demonstrating high TB risk (6%; exact 95% CI, 1%–19%). In some contexts, researchers may wish to supplement these research definitions with clinical decision data and longitudinal follow-up in order to improve specificity.

Original languageAmerican English
JournalOpen Forum Infectious Diseases
Volume8
DOIs
StatePublished - Jan 1 2021

Keywords

  • case definition
  • diagnosis
  • pediatric tuberculosis

Disciplines

  • Social and Behavioral Sciences
  • Social Work

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