Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru

Ruvandhi R. Nathavitharana, Cynthia X. Shi, Leonid. Chindelevitch, Roger Calderon, Zibiao Zhang, Jerome T Galea, Carmen C Contreras, Rosa Yataco, Leonid Lecca, Mercedes C Becerra, Megan B Murray, Ted Cohen

Research output: Contribution to journalArticlepeer-review

Abstract

Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB.

Original languageAmerican English
JournalEmerging Infectious Diseases
Volume23
DOIs
StatePublished - Nov 1 2017
Externally publishedYes

Disciplines

  • Social and Behavioral Sciences
  • Social Work

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