Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru

Ruvandhi R. Nathavitharana; Cynthia X. Shi; Leonid. Chindelevitch; Roger Calderon; Zibiao Zhang; Jerome T Galea; Carmen C Contreras; Rosa Yataco; Leonid Lecca; Mercedes C Becerra; Megan B Murray; Ted Cohen

doi:10.3201/eid2311.170077

Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru

Ruvandhi R. Nathavitharana, Cynthia X. Shi, Leonid. Chindelevitch, Roger Calderon, Zibiao Zhang, Jerome T Galea, Carmen C Contreras, Rosa Yataco, Leonid Lecca, Mercedes C Becerra, Megan B Murray, Ted Cohen

Research output: Contribution to journal › Article › peer-review

Abstract

Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB.

Original language	American English
Journal	Emerging Infectious Diseases
Volume	23
DOIs	https://doi.org/10.3201/eid2311.170077
State	Published - Nov 1 2017
Externally published	Yes

Disciplines

Social and Behavioral Sciences
Social Work

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Polyclonal Pulmonary Tuberculosis Infections and Risk for MultidrFinal published version, 1.01 MBLicense: CC BY

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title = "Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru",

abstract = " Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB.",

author = "Nathavitharana, \{Ruvandhi R.\} and Shi, \{Cynthia X.\} and Leonid. Chindelevitch and Roger Calderon and Zibiao Zhang and Galea, \{Jerome T\} and Contreras, \{Carmen C\} and Rosa Yataco and Leonid Lecca and Becerra, \{Mercedes C\} and Murray, \{Megan B\} and Ted Cohen",

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T1 - Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru

AU - Nathavitharana, Ruvandhi R.

AU - Shi, Cynthia X.

AU - Chindelevitch, Leonid.

AU - Calderon, Roger

AU - Zhang, Zibiao

AU - Galea, Jerome T

AU - Contreras, Carmen C

AU - Yataco, Rosa

AU - Lecca, Leonid

AU - Becerra, Mercedes C

AU - Murray, Megan B

AU - Cohen, Ted

PY - 2017/11/1

Y1 - 2017/11/1

N2 - Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB.

AB - Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB.

UR - https://digitalcommons.usf.edu/sok_facpub/13

U2 - 10.3201/eid2311.170077

DO - 10.3201/eid2311.170077

M3 - Article

C2 - 29048297

VL - 23

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

ER -

Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru

Abstract

Disciplines

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