TY - JOUR
T1 - The Confidence Information Ontology: A Step Towards a Standard for Asserting Confidence in Annotations
AU - Bastian, Frederic B.
AU - Chibucos, Marcus C.
AU - Gaudet, Pascale
AU - Giglio, Michelle
AU - Holiday, Gemma L.
AU - Huang, Hong
AU - Lewis, Suzanna E.
AU - Niknejad, Anne
AU - Orchard, Sandra
AU - Poux, Sylvain
AU - Skunca, Nives
AU - Robinson-Rechavi, Marc
AU - huang, hong
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Biocuration has become a cornerstone for analyses in biology, and to meet needs, the amount of annotations has considerably grown in recent years. However, the reliability of these annotations varies; it has thus become necessary to be able to assess the confidence in annotations. Although several resources already provide confidence information about the annotations that they produce, a standard way of providing such information has yet to be defined. This lack of standardization undermines the propagation of knowledge across resources, as well as the credibility of results from high-throughput analyses. Seeded at a workshop during the Biocuration 2012 conference, a working group has been created to address this problem. We present here the elements that were identified as essential for assessing confidence in annotations, as well as a draft ontology—the Confidence Information Ontology—to illustrate how the problems identified could be addressed. We hope that this effort will provide a home for discussing this major issue among the biocuration community.
AB - Biocuration has become a cornerstone for analyses in biology, and to meet needs, the amount of annotations has considerably grown in recent years. However, the reliability of these annotations varies; it has thus become necessary to be able to assess the confidence in annotations. Although several resources already provide confidence information about the annotations that they produce, a standard way of providing such information has yet to be defined. This lack of standardization undermines the propagation of knowledge across resources, as well as the credibility of results from high-throughput analyses. Seeded at a workshop during the Biocuration 2012 conference, a working group has been created to address this problem. We present here the elements that were identified as essential for assessing confidence in annotations, as well as a draft ontology—the Confidence Information Ontology—to illustrate how the problems identified could be addressed. We hope that this effort will provide a home for discussing this major issue among the biocuration community.
UR - https://digitalcommons.usf.edu/si_facpub/139
U2 - 10.1093/database/bav043
DO - 10.1093/database/bav043
M3 - Article
VL - 2015
JO - Database
JF - Database
ER -