TY - JOUR
T1 - The Need to Track Payment Incentives to Participate in HIV Research
AU - Brown, Brandon
AU - Galea, Jerome
AU - Dubé, Karine
AU - Davidson, Peter
AU - Khoshnood, Kaveh
AU - Holtzman, Lisa
AU - Marg, Logan
AU - Taylor, Jeff
PY - 2018/7/1
Y1 - 2018/7/1
N2 - Providing incentives is an accepted and common practice in human subjects research, including clinical HIV research. While we know that financial incentives among similar studies can greatly vary, surprisingly little research exists on how to determine when such incentives are excessive or constitute an “undue inducement.” Multiple factors, such as risks and benefits, study procedures, study budget, historical precedent, recommendations from institutional review boards, advice from other investigators, and local regulations may influence decisions about appropriate incentives, but little empirical data exist about what incentives are offered to potential research participants. Rules for acceptable gifts, services, and compensation should consider study location and population, but without a clearer understanding of currently offered incentives and how these practices match up to ethical beliefs of appropriateness, we continue to follow perceived trends without critical assessment. Here, we present one potential approach to explore the impact of financial incentives on biomedical HIV research and to further clarify undue inducement: the development of a framework to support ethical decision-making about payment to participate. This framework is based on input from people living with HIV, biomedical HIV researchers, ethicists, former study participants, and IRB members and includes a database that allows for tracking payment practices.
AB - Providing incentives is an accepted and common practice in human subjects research, including clinical HIV research. While we know that financial incentives among similar studies can greatly vary, surprisingly little research exists on how to determine when such incentives are excessive or constitute an “undue inducement.” Multiple factors, such as risks and benefits, study procedures, study budget, historical precedent, recommendations from institutional review boards, advice from other investigators, and local regulations may influence decisions about appropriate incentives, but little empirical data exist about what incentives are offered to potential research participants. Rules for acceptable gifts, services, and compensation should consider study location and population, but without a clearer understanding of currently offered incentives and how these practices match up to ethical beliefs of appropriateness, we continue to follow perceived trends without critical assessment. Here, we present one potential approach to explore the impact of financial incentives on biomedical HIV research and to further clarify undue inducement: the development of a framework to support ethical decision-making about payment to participate. This framework is based on input from people living with HIV, biomedical HIV researchers, ethicists, former study participants, and IRB members and includes a database that allows for tracking payment practices.
KW - HIV research
KW - research incentives
KW - payment to participate
KW - undue inducement
KW - human subjects research
KW - institutional review boards
UR - https://digitalcommons.usf.edu/sok_facpub/151
UR - https://www.thehastingscenter.org/irb_article/need-track-payment-incentives-participate-hiv-research/
M3 - Article
VL - 40
JO - IRB: Ethics & Human Research
JF - IRB: Ethics & Human Research
ER -